On the Zend Developer Zone today there's a new tutorial (by Jack Herrington) talking about working with Adobe AIR and Javascript to make a desktop application for uploading images (or any other files) to a remote server.
To solve the upload problem, most of the big services have dedicated upload applications that run on all the different platforms. But it takes a lot of work to develop them, especially when they have to run on both Macintosh and Windows. Or is it so tough? As it turns out, Adobe AIR technology makes it possible to write applications for any platform using just HTML and JavaScript. It also offers access to cool desktop features, notably drag and drop.
The tutorial shows how to make the application with the HTML/Javascript version of an AIR app (as opposed to Flex) that lets you drag and drop files into it to be uploaded. They make the basic file upload form first as a foundation then extend it to make it accept the remote request (via POST) from the AIR application to handle the uploads. Javascript code and screenshots are included.