In his latest post, Jim Plush looks at an Ajax/PHP framework that he has created that's lightweight and supports just the bare-bones of things - My-BIC.
2 lines of javascript and one php class are all you need to get an ajax setup going! So far it's for PHP5 however if there is interest in PHP4 I will create a quick version for that as well.
I'm looking for some volunteers to try it out and voice their opinions. The basic concept is:
one xmlhttp class that takes care of sending and receiving data and a php script on the server that acts as a front controller that all ajax requests go through.
He gives a code example in the post, and includes a graphic detailing how it all ties together. For more information on this simple framework, check out its current site.