In a recent blog post Akash Mehta showed how to reach into a Microsoft document (a Word file) and pull out the content inside via a PHP script.
Communicating via COM in PHP is easy as ever; especially for people coming from a VB background where executing complex tasks in MS-applications is a piece of cake, you will feel right at home in PHP. In fact, VB COM calls can be converted to PHP COM calls in just a few simple search and replaces.
He shows how to use the COM extension in a (Windows) PHP installation to access the text inside the document and manipulate the contents however you'd like (even writing them back out to another Word file).