Ivo Jansch has a new blog post today looking at a method he's come up with to debug command-line PHP applications in Eclipse PDT with their needed parameters (not as a stand-alone script).
I write quite a lot of command line utilities in PHP and luckily PDT makes it easy to debug command line scripts. The thing with command line scripts is that often they require parameters passed on the command line, and PDT offers an easy way to pass them when you debug a script.
He quickly illustrates (with a few screenshots) how to get the debugger to prompt for the values of the PHP script you've selected. You can also use a similar technique in other Eclipse-based IDEs (like Zend Studio or Aptana).