Joakim passed along a note today about a new web-based frontend for XDebug:
My about page has mentioned a web based frontend for Xdebug for some time. The project has a name now: The idea for Webgrind, a spin on Valgrind, came from lack of profiling tools for PHP, particularly on OSX. Though it is possible to install kcachegrind on osx it seems overkill for many uses and is definitely not as easy as unzipping a folder to the webroot.
He and Jacob Oettinger have started up the project and have posted some initial code over on the Google Code page for Webgrind. You can check out a screenshot of it in action here too.