On SitePoint.com today there's a new guide posted about how to get a WordPress instance up and running on an Amazon EC2 instance and the Microsoft Web Platform.

One claim I often hear from web developers, especially those who offer website design and consulting services, is their need to quickly launch websites that run fast and give them total control of the server for maximum flexibility and scalability. This is a quick tutorial on how to do just that, with a guided tour on how to run WordPress on Amazon’s EC2 Cloud and the Microsoft Web Platform. [...] WordPress and EC2 come together in a really slick way, giving you a super-fast blog or website in just a few minutes.

For those that don't already have an EC2 instance, he helps you get that set up first complete with an almost one-click install of a WordPress instance. With the help of the Web Platform Installer you can easily install not only WordPress but all of the other technology it needs to get running quickly. Screenshots accompany the tutorial descriptions to help make the whole process even simpler.